Resources

Case Study Champions' Patient-Derived Xenograft (PDX) Models for Evaluating Novel Therapeutics Targeting the DNA Damage Response Mechanism Download Now → (opens in a new tab) Infographic A Comparison of Syngeneic & Humanized Models in Oncology Research Download Now → (opens in a new tab) Infographic Species Immunophenotyping Guide Download Now → (opens in a new tab) Infographic Using Flow Cytometry from the Bench to the Clinic Download Now → (opens in a new tab) Infographic Implications of Matrix Use in 3D Tumor Cultures Download Now → (opens in a new tab) Case Study Champions' TumorGrafts® Guide the Development of a Novel, Selective Dual BRAF/EGFR Inhibitor, CEP-32496m Download Now → (opens in a new tab) Case Study Immunotherapy in Colon Cancer — Digesting the Facts Download Now → (opens in a new tab) Case Study Preclinical Evaluation of a Novel CAR T Therapy Using Champions' DLBCL PDX Models Download Now → (opens in a new tab) Case Study Using Champions' PDX Models for Preclinical Validation of ERK Pathway Inhibitors Download Now → (opens in a new tab) Case Study Using Champions' PDX Models for Preclinical Validation of HER2-Specific Small Molecule Inhibitors Download Now → (opens in a new tab) Case Study Using Champions' Prostate PDX Models for Preclinical Validation of a Novel, PSMA-directed BiTE Download Now → (opens in a new tab) Flow Cytometry Panel Complex Immunophenotyping Panel I Download Now → (opens in a new tab) Flow Cytometry Panel Complex Immunophenotyping Panel II Download Now → (opens in a new tab) Flow Cytometry Panel Complex Macrophage Immunophenotyping Panel Download Now → (opens in a new tab) Flow Cytometry Panel Complex Effector Cytolytic Panel Download Now → (opens in a new tab) Flow Cytometry Panel Complex B Cell Immunophenotyping Panel Download Now → (opens in a new tab) Flow Cytometry Panel Complex NK Cell Immunophenotyping Panel Download Now → (opens in a new tab) Flow Cytometry Panel Comprehensive T Cell Checkpoint Panel Download Now → (opens in a new tab) Flow Cytometry Panel Receptor Occupancy Assessment Download Now → (opens in a new tab) Flow Cytometry Panel PhenoSeek AML Download Now → (opens in a new tab) Model Spotlight CTG-2842: A NSCLC Exon 20 EGFR Mutated Model Download Now → (opens in a new tab) Model Spotlight CTG-2992: A NSCLC Exon 20 EGFR Mutated Model Download Now → (opens in a new tab) PDX Model Cohort Acute Myeloid Leukemia Download Now → (opens in a new tab) PDX Model Cohort B Cell Acute Lymphoblastic Leukemia Download Now → (opens in a new tab) PDX Model Cohort Biliary Tract Cancer Download Now → (opens in a new tab) PDX Model Cohort Bladder Cancer Download Now → (opens in a new tab) PDX Model Cohort Breast Cancer Download Now → (opens in a new tab) PDX Model Cohort Colorectal Cancer Download Now → (opens in a new tab) PDX Model Cohort Gastric Cancer Download Now → (opens in a new tab) PDX Model Cohort Glioblastoma Download Now → (opens in a new tab) PDX Model Cohort Head & Neck Cancer Download Now → (opens in a new tab) PDX Model Cohort Hepatocelllular Download Now → (opens in a new tab) PDX Model Cohort HER2+ Download Now → (opens in a new tab) PDX Model Cohort Melanoma Download Now → (opens in a new tab) PDX Model Cohort Diffuse Large B Cell & Non-Hodgkin's Lymphoma Download Now → (opens in a new tab) PDX Model Cohort Non-Small Cell Lung Cancer Download Now → (opens in a new tab) PDX Model Cohort Ovarian Cancer Download Now → (opens in a new tab) PDX Model Cohort Pancreatic Cancer Download Now → (opens in a new tab) PDX Model Cohort Prostate Cancer Download Now → (opens in a new tab) PDX Model Cohort Renal Cell Carcinoma & Kidney Cancer Download Now → (opens in a new tab) PDX Model Cohort Sarcoma Download Now → (opens in a new tab) Poster CYTO 2025: Considerations for Global Harmonization and Quality Assessments using spectral flow cytometers Download Now → (opens in a new tab) Poster CYTO 2024: Development and Validation of a 29-Color Immunophenotyping panel for the 3-laser Cytek Northern Lights Download Now → (opens in a new tab) Poster CYTO 2024: Evaluation of PBMC Isolation Methods and the Impact of Cryopreservation Download Now → (opens in a new tab) Poster AACR 2024: Immunophenotyping via High Complexity Flow Cytometry in Acute Myeloid Leukemia Download Now → (opens in a new tab) Poster SITC 2023: Development of a Flow Cytometric Receptor Occupancy Assay for Clinical Analysis of Immune Checkpoint Inhibitor Therapeutics Download Now → (opens in a new tab) Poster SITC 2024: Primary, Fully Characterized Autologous AML System allows the Correlation of T Cell Activation with Leukemia Cell Survival upon Io Treatment in a Novel Autologous System Download Now → (opens in a new tab) Poster AACR 2024: Systematic Analysis of Gene Mutations and Therapeutic Efficacy via Ex vivo Hematological VitroScreen Platform Download Now → (opens in a new tab) Poster AACR 2024: Unveiling the Correlation between gemtuzumab-ozogamicin Efficacy and CD33+ Expression in AML Primary Samples Using the Novel AML VitroScreen Download Now → (opens in a new tab) Poster AACR 2023: Ex Vivo Modeling of Multiple Myeloma: A Novel Drug Sensitivity Screening Platform Download Now → (opens in a new tab) Poster AACR 2021: In Vitro Drug Sensitivity Screening Platform for Chronic Lymphocytic Leukemia (CLL) Patient Samples Download Now → (opens in a new tab) Poster AACR 2021: In Vitro and In Vivo Model for Evaluation of Novel Therapeutic Agents in Patient-derived Lymphoblastic Leukemia (B-ALL) Download Now → (opens in a new tab) Poster AACR 2020: 2D Ex Vivo Patient-Derived Acute Myeloid Leukemia Platform for Evaluation of Novel Molecular Targeted Therapeutic Agents Download Now → (opens in a new tab) Poster SITC 2023: Development of a Non-small cell lung cancer PDX model in a myeloid-boosted humanized host highlights an M2 polarization phenotype within the myeloid compartment Download Now → (opens in a new tab) Poster SITC 2023: A Novel Gene Signature predicts immune infiltration phenotypes in humanized Patient-Derived Xenograft Models Download Now → (opens in a new tab) Poster AACR 2020: Natural Killer (NK) Human Immune System (HIS) ImmunoGraft® Platform to Evaluate the Pharmacodynamics of Immuno-Oncology Therapeutics Download Now → (opens in a new tab) Poster NYAS 2019: Unique Immunodeficient Murine Host Strains Impact Expansion and Engraftment of T Cells in PBMC Humanized Mice Download Now → (opens in a new tab) Poster SITC 2019: Development of a Peripheral Blood Mononuclear Cells (PBMC) ImmunoGraft® Platform to Evaluate of the Pharmacodynamics of Immuno Oncology Therapeutics Download Now → (opens in a new tab) Poster SITC 2023: Computational deconvolution identifies a Th2-enriched immune-inflammatory signature in invasive breast carcinoma Download Now → (opens in a new tab) Poster AACR 2023: A Pharmaco-Pheno-Multiomic Integration Analysis of Pancreatic Cancer: A Highly Predictive Biomarker Model of Biomarkers of Gemcitabine/Abraxane Sensitivity and Resistance Download Now → (opens in a new tab) Poster AACR 2023: Multiomic Approaches to Illuminate Molecular Drivers of Breast Cancer Metastasis to the Liver Download Now → (opens in a new tab) Poster AACR 2022: A Pharmaco-Pheno-Multiomic Integration Analysis of Primary Acute Myeloid Leukemia Reveals Biomarkers of Cytarabine Resistance Download Now → (opens in a new tab) Poster AACR 2022: Pharmaco-Pheno-Multiomic Integration Builds A Biomarker Network of Olaparib Resistance in Ovarian Cancer Download Now → (opens in a new tab) Poster Tumor Models San Francisco 2025: An Integrated Platform for Antibody-Drug Conjugate Discovery and Development Download Now → (opens in a new tab) Poster AACR 2024: Mutational signatures in PDXs for improved understanding of drug response and companion biomarkers identification Download Now → (opens in a new tab) Poster AACR 2024: A Novel Gene Signature predicting fibroblast composition in the TME allows for an improved selection of PDX models for preclinical studies Download Now → (opens in a new tab) Poster AACR 2023: Raptamer-Drug Conjugates as Molecularly Targeted Cancer Therapeutics Download Now → (opens in a new tab) Poster San Antonio Breast Cancer Symposium 2022: Combining Multiomics and Histological Assessment to Identify Patient-derived Xenograft Models of Invasive Lobular Carcinoma Download Now → (opens in a new tab) Poster AACR 2024: Bioluminescent 3D Tumors with Immune Cell Co-culture for High Throughput Screening (HTS) Download Now → (opens in a new tab) Poster AACR 2024: Tumor-on-Chip Co-culture System: An Innovative Tool in Personalized Medicine to Investigate Cancer Progression Download Now → (opens in a new tab) Poster AACR 2024: A Novel 3D Co-Culture Platform for Patient-Specific Immune-Oncology Treatment Download Now → (opens in a new tab) Poster AACR 2024: An Innovative PDX and Patient-derived 3D Platform for Improved Translatability of New Medical Entities Download Now → (opens in a new tab) Poster SITC 2023: A Novel TumorGraft3D immune co-culture platform for high throughput immune-oncology screening Download Now → (opens in a new tab) Poster SITC 2023: Establishment of Tumor-on-Chip system to study the role of tumor microenvironment on cancer progression in a patient-specific manner Download Now → (opens in a new tab) Poster Tumor Models Boston 2023: Identification of synergistic combination of molecular targeted agents and chemotherapy using TumorGraft3D and Lumin platform Download Now → (opens in a new tab) Poster AACR 2021: Unique 3D Organoids Autologous TIL Co-Culture Platform Enables High Throughput Immune-Oncology Drug Response Studies Download Now → (opens in a new tab) Poster SITC 2021: 3D Co-Culture Platform Reveals Insights into Patient Autologous Immune Cell-Tumor Interaction and Immune Modulation In Vitro Download Now → (opens in a new tab) Poster SITC 2020: Development of a 3D Organoid Autologous TIL Co-Culture Platform for High Throughput Immuno-Oncology Studies Download Now → (opens in a new tab) Service Overviews Autologous AML Download Now → (opens in a new tab) Service Overviews Autologous Tumor Infiltrating Lymphocyte (TIL) Download Now → (opens in a new tab) Service Overviews Histology & Immunohistochemistry (IHC) Download Now → (opens in a new tab) Service Overviews Humanized Models Download Now → (opens in a new tab) Service Overviews Next Generation Sequencing Download Now → (opens in a new tab) Service Overviews Preclinical In Vivo Imaging in Systemic Tumor Models Download Now → (opens in a new tab) Service Overviews 4D Proteomics Download Now → (opens in a new tab) Service Overviews TumorGraft3D Download Now → (opens in a new tab) Service Overviews Western Blot Download Now → (opens in a new tab) White Paper Flow Cytometry in the Clinic: Benefits, Challenges, & Opportunities Download Now → (opens in a new tab) White Paper Hematologic Malignancies: Immunogenomic Landscape & Prognostic Tools Download Now → (opens in a new tab) White Paper Bench to Bedside Innovations: Understanding Cancer with Patient-Derived Xenografts (PDX) Download Now → (opens in a new tab) Poster AACR 2025: Advancing CAR-Ts and anti-immunosuppressive therapy development: Immunosuppressive TME 3D co-culture platform grounded on a fully characterized PDX tumor Bank Download Now → (opens in a new tab) Poster AACR 2025: Clinical relevance and translatability of NSCLC patient-derived xenograft (PDX) models for evaluating cMET-targeted therapies Download Now → (opens in a new tab) Poster AACR 2025: High throughput phenotyping and drug discovery using the TumorGraft3D co-culture platform and flow cytometry Download Now → (opens in a new tab) Poster AACR 2025: Investigating the efficacy of 177-Lu therapeutics in a series of Castrate Resistant Prostate Cancer PDX Models Download Now → (opens in a new tab) Poster AACR 2025: Comparative analysis of mutational signatures in TumorGraft PDX bank and TCGA dataset to improve patient tumor modeling Download Now → (opens in a new tab) Poster AACR 2025: Multi-omics and histological assessment to identify patient-derived xenograft models of invasive lobular carcinoma Download Now → (opens in a new tab) Poster AACR 2025: Building 3D ex vivo models as a powerful platform for anti-cancer drug and biomarker discovery Download Now → (opens in a new tab) Poster AACR 2025: HER2-positive patient-derived xenograft organoids (PDXOs) as a novel preclinical tool to evaluate new therapies against HER2-driven cancers Download Now → (opens in a new tab) Poster AACR 2025: High-throughput screening of clinically relevant patient-derived 3D cultures to inform on the efficacy of Antibody Drug Conjugate Payloads in 10 distinct cancer indications Download Now → (opens in a new tab) Poster AACR 2025: Establishment of an orthotopic intracranial luciferase labelled patient-derived xenograft of glioblastoma in immunocompromised mice model Download Now → (opens in a new tab) Poster AACR 2025: Leveraging the tumor microenvironment (TME) atlas to identify the best PDX model for pre-clinical testing of TME targeting agents Download Now → (opens in a new tab) Poster AACR 2025: Targeted immunotherapies in Multiple Myeloma: focus on flow cytometry markers and therapeutic implications Download Now → (opens in a new tab) Poster AACR 2025: An integrated preclinical platform for Antibody-Drug Conjugate development Download Now → (opens in a new tab) Poster AACR 2025: Predicting clinical checkpoint inhibitor responses with TumorGraft3D PBMC co-culture Download Now → (opens in a new tab) Poster AACR 2025: Development of an HLA-matched humanized immune system mouse model with primary AML patient samples for immunotherapy testing Download Now → (opens in a new tab) Webinar Integrating Functionalized Multi-omics in Oncology Drug Discovery Watch Now → (opens in a new tab) Webinar How to Use Primary Patient Samples in Preclinical Models to Improve Translational Relevance in Blood Cancer Research Watch Now → (opens in a new tab) Webinar How to Design a Successful 3D Tumor Model Co-Culture Study Watch Now → (opens in a new tab) Webinar Poster QuickTake: A Novel Gene Signature predicting TME Fibroblast Composition Watch Now → (opens in a new tab) Webinar Poster QuickTake: Mylotarg Efficacy and CD33+ Expression in AML Correlation Watch Now → (opens in a new tab) Webinar Receptor Occupancy Assays: A Comprehensive Guide for Clinical Trial Success Watch Now → (opens in a new tab) Webinar Poster QuickTake: Immunophenotyping via High Complexity Flow Cytometry in AML Watch Now → (opens in a new tab) Webinar Poster QuickTake: Systematic Analysis of Mutations & Efficacy via VitroScreen Watch Now → (opens in a new tab) Webinar Poster QuickTake: Bioluminescent 3D Tumors with Immune Cell Co-culture for HTS Watch Now → (opens in a new tab) Webinar Poster QuickTake: Tumor-on-Chip Co-culture System Watch Now → (opens in a new tab) Webinar Discover TumorGraft3D: A Technical Deep-Dive for Advancing Oncology Research Watch Now → (opens in a new tab) Webinar Poster QuickTake: Mutational Signatures in PDXs for biomarker identification Watch Now → (opens in a new tab) Webinar Mastering Precision in Clinical Specialty Testing: The Impact of PBMC Isolation Watch Now → (opens in a new tab) Webinar Autologous Co-culture Models to Humanized Mouse Models: Navigating IO Models Watch Now → (opens in a new tab) Webinar The Power of Global Standardization: Unlock High Quality Flow Cytometry Results Watch Now → (opens in a new tab) Webinar Identify MOA and Companion Biomarkers in Oncology using Multi-Omic Analyses Watch Now → (opens in a new tab) Webinar Radiotracers and ADC Targeting: Scientific Insights for In Vivo Validation and Clinical Transition Watch Now → (opens in a new tab) Webinar Mapping the Cell Surface Proteome: Transforming Drug Target Discovery and Translational Modeling in Oncology Watch Now → (opens in a new tab) Poster SITC 2025 Poster 1245: Evaluating the Efficacy of Targeted Therapies in HER2-Driven Cancers Using Patient-Derived Xenograft Organoids Download Now → (opens in a new tab) Poster SITC 2025 Poster 1244: Modeling the Immunosuppressive Tumor Microenvironment for CAR-T Development: A Patient-Derived 3D Co-Culture Platform with CAFs and M2 Macrophages Download Now → (opens in a new tab) Poster SITC 2025 Poster 992: Development of a Clinically Relevant Organoid-Based ADCC Co-Culture Platform for Preclinical Evaluation of Fc-Competent Antibody Therapeutics Download Now → (opens in a new tab) Poster SITC 2025 Poster 316: A Humanized In Vivo Platform for Modeling Primary Acute Myeloid Leukemia to Advance Immunotherapy, Bispecific, and CAR-T Cell Development Download Now → (opens in a new tab) Poster SITC 2025 Poster 148: DRUG-seq in CTG3D Organoid Models: A High-Throughput, Transcriptomics-Driven Platform for AI-Enhanced Drug Discovery Download Now → (opens in a new tab) Poster TRP Europe 2025 Poster: Advancing Radiopharmaceutical Development with Translationally Relevant PDX Models Download Now → (opens in a new tab) Poster World ADC 2025: An Integrated Preclinical Platform for Antibody-Drug Conjugate Development Download Now → (opens in a new tab) Case Study Assessment of Clinically Approved HER2-Targeted ADCs in Champions’ TumorGraft3D Models Download Now → (opens in a new tab) Poster AACR 2026 Poster 7214: LymphGen-Based Stratification of DLBCL PDX Models Mirrors Clinical Tumor Complexity Download Now → (opens in a new tab) Poster AACR 2026 Poster 7213: Evaluation of folate receptor-alpha antibody-drug conjugate mirvetuximab soravtansine-gynx in ovarian cancer PDXs Download Now → (opens in a new tab) Poster AACR 2026 Poster 7174: CAR T-Cell therapy efficacy evaluation in TumorGraft3D tri-culture platform with reconstructed tumor microenvironment Download Now → (opens in a new tab) Poster AACR 2026 Poster 6415: Scalable chem-seq and functional-seq platforms for profiling chemical and genetic perturbations in patient-derived organoids Download Now → (opens in a new tab) Poster AACR 2026 Poster 5812: Preclinical evaluation of [177Lu] Lu-PSMA-617 and [225Ac] Ac-PSMA-617 in mice bearing castration-resistant prostate adenocarcinoma patient-derived xenografts Download Now → (opens in a new tab) Poster AACR 2026 Poster 4868: Modelling glioblastoma sensitivity to irradiation with a patient derived xenograft-derived 3D platform Download Now → (opens in a new tab) Poster AACR 2026 Poster 2832: Evaluation of Natural Killer cells’ Contribution to the Efficacy of Immuno-oncology Regimens in Patient Derived Xenograft-Derived 3D Models Download Now → (opens in a new tab) Poster AACR 2026 Poster 1884: Molecular determinants of sensitivity and resistance to the pan-RAS(ON) inhibitor daraxonrasib (RMC-6236) across KRAS-mutant patient-derived models Download Now → (opens in a new tab) Poster CYTO 2026 Poster P003: A High-Dimensional Spectral Flow Cytometry Panel Incorporating Open-Channel Design to Enable Comprehensive Profiling of Human Immune Cell Heterogeneity in Peripheral Blood and PBMCs Download Now → (opens in a new tab) Poster CYTO 2026 Poster P011: Development of Robust Evaluation of T Cell Subsets with T-Cell Activation In a 3D Tumor–PBMC Co-Culture Model Enables Reliable Phenotyping and Cytotoxicity Assessment Download Now → (opens in a new tab) Webinar Cracking KRAS: Decoding Sensitivity and Resistance to Pan-RAS(ON) Inhibition Across Patient-Derived Tumour Models Watch Now → (opens in a new tab) Service Overviews Mouse Clinical Trials Download Now → (opens in a new tab) Service Overviews Clinically Relevant, Patient-Derived Xenograft Models Download Now → (opens in a new tab) White Paper A Multi-Omic Framework for Understanding KRAS Inhibitor Response Download Now → (opens in a new tab) Webinar Targeting KRAS mutations: Latest therapeutic approaches and clinical insights Watch Now → (opens in a new tab) Service Overviews In-House, U.S.-Based MicroSPECT/CT Imaging for Radiopharmaceutical Development Download Now → (opens in a new tab)