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Webinar

How to Use Primary Patient Samples in Preclinical Models to Improve Translational Relevance in Blood Cancer Research

Summary

Hematologic research faces critical challenges that hinder effective blood cancer treatments. One major issue is the use of traditional animal models, which often don't accurately reflect human disease, leading to misleading results and higher clinical trial failure rates.

Additionally, blood cancer's complexity, with genetic diversity and changing tumor environments, poses significant obstacles to understanding the disease and finding key biomarkers. This comprehensive webinar will guide you through effective strategies to mitigate these challenges by leveraging Champions’ unparalleled bank of hematological models:

Key Topics:

  • Model Selection

    How do you find the most clinically relevant models?

  • Primary or Passaged Models

    What gives you the most biologically relevant results?

  • Ex vivo or In vivo Modeling

    What type of study best replicates the complex tumor environment?

  • Successful Applications

    Case studies demonstrating how you can accelerate your research

The Presenter

stefanos

Sr. Global Scientific Director at Champions Oncology

Stefano Cairo, PhD

Stefano Cairo, PhD has extensive experience in the field of oncology and rare diseases. Stefano is currently serving as the Senior Global Scientific Director at Champions Oncology, Inc. Prior to this, they held the position of Head of Research and Development at XenTech, where they led multiple projects focused on molecular and pharmaceutical characterization of preclinical models and establishing a preclinical cohort for pediatric liver cancer. Stefano also worked as a Researcher at the University of Ferrara and as a Post-doctoral fellow at Institut Pasteur, where they specialized in the molecular and functional characterization of hepatoblastoma. Stefano began their career as a PhD student and post-doc at Tigem, focusing on the identification and functional characterization of genes related to rare human diseases and cancer.

Stefano Cairo, PhD, began their education in 1985 at Liceo Scientifico Bertrand Russell in Italy, where they obtained their High School Diploma in an unspecified field of study. Stefano then pursued their undergraduate studies in Biology at Università degli Studi di Milano from 1990 to 1996, earning a Master of Arts (MA) degree. Continuing their academic journey, they attended The Open University from 2001 to 2004, specializing in Biology with a focus on human genetics, culminating in the completion of a Doctor of Philosophy (PhD) degree in this field.

Watch the webinar