Colorectal Cancer In Vivo Screen
Champions' new Colorectal Cancer (CRC) In Vivo Screen comprises 30 distinct CRC models, each thoroughly characterized with patient response data and clinical annotations. These models also include NGS (WES and RNA-seq) data, available in Lumin.
This unique set of CRC models represent different treatments and genetic profiles and includes models with KRAS and BRAF mutations, and with ERBB2 amplification.
CRC Model Clinical and Molecular Characteristics

Response to Standards of Care

BRAF - KRAS - ERBB2 Oncoprint

CRC In Vivo Screen highlights:
- 30 unique CRC PDX models
- Increased cost saving compared to standalone studies
- 50% off of a Standard of Care agent arm (selected by Champions)
- No minimum number of models to enroll and you have the ability to select the models you want to screen
- Flow Cytometry and IHC are available upon request.
- Terminal tumor collections (Snap Frozen/FFPE) for target validation available upon request.
- Full model characterization (clinical data and NGS) is available for data analysis and visualization using Lumin
Request More Information About the CRC In Vivo Screen