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Always at the forefront of the dynamic patient-derived xenograft (PDX) market, Champions Oncology has emerged as a respected key opinion leader on the utilization and benefits of PDX models in oncology drug development.

Always at the forefront of the dynamic patient-derived xenograft (PDX) market, Champions Oncology has emerged as a respected key opinion leader on the utilization and benefits of PDX models in oncology drug development.

Clinical Flow Cytometry
Hematological Malignancies
Humanized Models
Lumin Acuity
Solid Tumor PDX Models
TumorGraft3D & Co-Culture Platforms

Advancing CAR-Ts and anti-immunosuppressive therapy development: Immunosuppressive TME 3D co-culture platform grounded on a fully characterized PDX tumor Bank - AACR 2025

Comparative analysis of mutational signatures in TumorGraft PDX bank and TCGA dataset to improve patient tumor modelingAACR 2025

Building 3D ex vivo models as a powerful platform for anti-cancer drug and biomarker discoveryAACR 2025

HER2-positive patient-derived xenograft organoids (PDXOs) as a novel preclinical tool to evaluate new therapies against HER2-driven cancers - AACR 2025

High-throughput screening of clinically relevant patient-derived 3D cultures to inform on the efficacy of Antibody Drug Conjugate Payloads in 10 distinct cancer indicationsAACR 2025

Predicting clinical checkpoint inhibitor responses with TumorGraft3D PBMC co-cultureAACR 2025

Primary, fully characterized autologous AML system allows the correlation of T cell activation with leukemia cell survival upon IO treatment in a novel autologous system - SITC 2024

Bioluminescent 3D Tumors with Immune Cell Co-culture for High Throughput Screening (HTS) - AACR 2024

Tumor-on-Chip Co-culture System: An Innovative Tool in Personalized Medicine to Investigate Cancer Progression - AACR 2024

A Novel 3D Co-Culture Platform for Patient-Specific Immune-Oncology Treatment - AACR 2024

An Innovative PDX and Patient-derived 3D Platform for Improved Translatability of New Medical Entities - AACR 2024

A Novel TumorGraft3D immune co-culture platform for high throughput immune-oncology screening - SITC 2023

Establishment of Tumor-on-Chip system to study the role of tumor microenvironment on cancer progression in a patient-specific manner - SITC 2023

Identification of synergistic combination of molecular targeted agents and chemotherapy using TumorGraft3D and Lumin platform - Tumor Models Boston 2023

Unique 3D Organoids Autologous TIL Co-Culture Platform Enables High Throughput Immune-Oncology Drug Response Studies - AACR 2021

3D Co-Culture Platform Reveals Insights into Patient Autologous Immune Cell-Tumor Interaction and Immune Modulation In Vitro - SITC 2021

Development of a 3D Organoid Autologous TIL Co-Culture Platform for High Throughput Immuno-Oncology Studies - SITC 2020