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PDX Model Cohort

Head & Neck CancerPDX Models (HNSCC)

Access one of the largest collections of clinically relevant head &amp; neck cancer PDX models, expertly curated to assess the therapeutic potential of your novel drug candidates.

Summary

Champions' Head & Neck  Cancer PDX Models represent a premier cohort designed to advance the discovery of breakthrough therapies for head and neck cancers. With one of the industry's largest banks of HNSCC models, this collection includes 125* Patient-Derived Xenograft (PDX) models that preserve critical clinical and molecular characteristics, mutation profiles, and pretreated models exposed to the latest cancer therapies, offering a powerful platform to evaluate the efficacy and therapeutic potential of drug candidates.

(*Model numbers fluctuate as our dataset continuously evolves.)

  • Access one of the largest banks of HNSCC models with clinically relevant molecularand pathological characteristics on the market.

  • Includes models pretreated with advanced cancer therapies and those resistant to targeted treatments and the latest immunotherapies targeting CDK4, PI3K, and EGFR.

  • Access to highly characterized HNSCC models with High Complexity Flow Cytometry, WES, RNAseq, Proteomics, and Phosphoproteomics.

  • Features models retaining key mutation profiles and clinical cancer characteristics, such as models that are HPV16+ and/or HPV18+.

Clinically Relevant Models

Living & diverse bank of clinically relevant models that correlate with clinical outcomes

Pretreated PDX Models

Established from tumor biopsies from patients pretreated with latest generation therapies

Multi-omic Characterization

Clinical annotations coupled with molecular datasets and in vivo responses

Download the model cohort