PDX Model Cohort
Colorectal Cancer PDX Models (CRC)
An extensive bank of Colorectal Cancer PDX Models directly established from primary, metastatic tumors, and pretreated patient tumors available for drug development research.
Summary
Champions Oncology has established an advanced cohort of 190* Colorectal Cancer PDX models, providing a comprehensive platform for translational CRC research. As one of the largest Colorectal Cancer patient-derived xenograft repositories in the industry, these models are directly developed from primary patient biopsies, preserving key molecular and clinical features, including real-world mutations and therapy responses, making them extremely rare and clinically relevant.
(*Model numbers fluctuate as our dataset continuously evolves.)
Champions' advanced colorectal cancer cohort showcases low-passage PDX models, each reflecting key clinical characteristics, mutations, and pretreatment history.
Access to one of the largest banks of 190 clinically relevant colorectal cancer PDX models retaining key molecular and pathological characteristics on the market.
Access to highly characterized models with High Complexity Flow Cytometry, WES, RNAseq, Proteomics, and Phosphoproteomics.
More than 75% of the CRC models have been pretreated, having been exposed to a wide range of treatments, from chemotherapy to targeted inhibitors, alone or in combination.