Mutational signatures in PDXs for improved understanding of drug response and companion biomarkers identification

Systematic Analysis of Gene Mutations and Therapeutic Efficacy via Ex vivo Hematological VitroScreen Platform

A Novel Gene Signature predicting fibroblast composition in the TME allows for an improved selection of PDX models for preclinical studies

Unveiling the Correlation between gemtuzumab-ozogamicin Efficacy and CD33+ Expression in AML Primary Samples Using the Novel AML VitroScreen

Bioluminescent 3D Tumors with Immune Cell Co-culture for High Throughput Screening (HTS)

Tumor-on-Chip Co-culture System: An Innovative Tool in Personalized Medicine to Investigate Cancer Progression

A Novel 3D Co-Culture Platform for Patient-Specific Immune-Oncology Treatment

An Innovative PDX and Patient-derived 3D Platform for Improved Translatability of New Medical Entities

Immunophenotyping via High Complexity Flow Cytometry in Acute Myeloid Leukemia

Development of a Flow Cytometric Receptor Occupancy Assay for Clinical Analysis of Immune Checkpoint Inhibitor Therapeutics - SITC 2023

Ex Vivo Modeling of Multiple Myeloma: A Novel Drug Sensitivity Screening Platform - AACR 2023

In Vitro Drug Sensitivity Screening Platform for Chronic Lymphocytic Leukemia (CLL) Patient Samples - AACR 2021

In Vitro and In Vivo Model for Evaluation of Novel Therapeutic Agents in Patient-derived Lymphoblastic Leukemia (B-ALL) - AACR 2021

2D Ex Vivo Patient-Derived Acute Myeloid Leukemia Platform for Evaluation of Novel Molecular Targeted Therapeutic Agents - AACR 2020

Development of a Non-small cell lung cancer PDX model in a myeloid-boosted humanized host highlights an M2 polarization phenotype within the myeloid compartment - SITC 2023

A Novel Gene Signature predicts immune infiltration phenotypes in humanized Patient-Derived Xenograft Models - SITC 2023

Natural Killer (NK) Human Immune System (HIS) ImmunoGraft^® Platform to Evaluate the Pharmacodynamics of Immuno-Oncology Therapeutics - AACR 2020

Unique Immunodeficient Murine Host Strains Impact Expansion and Engraftment of T Cells in PBMC Humanized Mice - NYAS 2019

Development of a Peripheral Blood Mononuclear Cells (PBMC) ImmunoGraft^® Platform to Evaluate of the Pharmacodynamics of Immuno Oncology Therapeutics - SITC 2019

Computational deconvolution identifies a Th2-enriched immune-inflammatory signature in invasive breast carcinoma - SITC 2023

A Pharmaco-Pheno-Multiomic Integration Analysis of Pancreatic Cancer: A Highly Predictive Biomarker Model of Biomarkers of Gemcitabine/Abraxane Sensitivity and Resistance - AACR 2023

Multiomic Approaches to Illuminate Molecular Drivers of Breast Cancer Metastasis to the Liver - AACR 2023

A Pharmaco-Pheno-Multiomic Integration Analysis of Primary Acute Myeloid Leukemia Reveals Biomarkers of Cytarabine Resistance - AACR 2022

Pharmaco-Pheno-Multiomic Integration Builds A Biomarker Network of Olaparib Resistance in Ovarian Cancer - AACR 2022

Raptamer-Drug Conjugates as Molecularly Targets Cancer Therapeutics - AACR 2023

Combining Multiomics and Histological Assessment to Identify Patient-derived Xenograft Models of Invasive Lobular Carcinoma - San Antonio Breast Cancer Symposium 2022

A Novel TumorGraft3D immune co-culture platform for high throughput immune-oncology screening - SITC 2023

Establishment of Tumor-on-Chip system to study the role of tumor microenvironment on cancer progression in a patient-specific manner - SITC 2023

Identification of synergistic combination of molecular targeted agents and chemotherapy using TumorGraft3D and Lumin platform - Tumor Models Boston 2023

Unique 3D Organoids Autologous TIL Co-Culture Platform Enables High Throughput Immune-Oncology Drug Response Studies - AACR 2021

3D Co-Culture Platform Reveals Insights into Patient Autologous Immune Cell-Tumor Interaction and Immune Modulation In Vitro - SITC 2021

Development of a 3D Organoid Autologous TIL Co-Culture Platform for High Throughput Immuno-Oncology Studies - SITC 2020