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Next Generation Sequencing (NGS) Services 

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NGS Services for Preclinical & Clinical Applications

Champions' experts can help you integrate Whole Exome Sequencing (WES), RNA sequencing (RNAseq), Digital RNA with pertUrbation of Genes sequencing (DRUG-seq), or Whole Transcriptome Sequencing (WTS) into your preclinical studies or clinical trials to discover endless insights.

  • Tissue processing is available following post-study completion at our US-based facility
  • Fast turnaround times with reliable, high-quality data analysis
  • Data analysis and visualization are delivered through Lumin or analyzed by Champions' dedicated team of bioinformaticians

Uncover Deep Molecular Insights using Preclinical Next Generation Sequencing 

 

Next Generation Sequencing (NGS) can be utilized as an endpoint for in vivo and ex vivo studies to provide a deeper understanding of the model to better stratify responders versus non-responders and to discover novel biomarkers to guide patient selection. 

In particular, DRUG-seq can be used to study an agent's effect on the transcriptome and investigate mechanisms of action and profiles of drug response and resistance, using limited starting material.

As oncology experts, our team has deep scientific competencies to not only aid in the planning of your upcoming in vivo or ex vivo study, but to recommend NGS endpoint analyses that can help you discover powerful insights with your therapeutic candidate from our highly characterized tumor bank.

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NGS for Clinical Applications

Champions provides Next Generation Sequencing (NGS) as an exploratory endpoint for your clinical trials.

GCLP-compliant sample processing at our global facilities provides fast turnaround times with reliable, high-quality data analysis delivered using a secure cloud-based platform. 

Champions computational biology experts also provides custom bioinformatic analysis through Lumin Acuity.

 
Next Generation Sequencing (NGS) is an innovative technology that has revolutionized oncology research. Specifically, with NGS technology researchers are able to quickly sequence all exons in a genome (Whole Exome Sequencing or WES) and utilize RNA sequencing (RNA-Seq) to discover novel RNA variants and quantify mRNA for differential gene expression analysis. Download this platform sheet to learn more about Champions' NGS offering. 

 

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