CDX
UM-UC-14
Tumor indication
Kidney
Tumor subtype
Transitional Cell Carcinoma
Description
UM-UC-14 (Bladder Cancer CDX Model)
The UM-UC-14 line was derived from a human urothelial carcinoma of the bladder. It represents advanced bladder cancer biology. UM-UC-14 is widely used in drug testing and biomarker development. Its reproducibility ensures reliability in bladder cancer pipelines.
Key Features:
- Derived from human urothelial carcinoma.
- Represents advanced bladder cancer.
- Epithelial morphology.
- Tumorigenic in xenografts.
Applications:
UM-UC-14 supports therapeutic discovery in bladder cancer. Researchers apply it in biomarker validation and drug resistance studies. It is used to test cytotoxic and targeted therapies in urothelial carcinoma. Its consistent growth makes it reliable for translational research.
Details
- Tumor indication
- Kidney
- Tumor subtype
- Transitional Cell Carcinoma
- Organism
- Human
- Mouse sex
- Female
Mutated genes
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Gene expression
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| Gene | Expression |
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Expression measured across the Champions panel.
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