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CDX

U-87 MG

Description

U-87 MG (Glioblastoma CDX Model) 

The U-87 MG line was derived from a glioblastoma of the brain. It represents one of the most aggressive brain cancers. U-87 MG has been extensively used in neuro-oncology drug development. Its reproducibility ensures value in translational glioblastoma research. 

Key Features: 

  • Derived from human glioblastoma. 
  • Highly proliferative brain tumor line. 
  • Aggressive xenograft growth. 
  • Represents advanced glioblastoma biology. 

Applications: 
U-87 MG supports therapeutic development in glioblastoma. Researchers apply it in biomarker validation and resistance mechanism studies. It is also used in testing drug delivery strategies for brain tumors. Its reproducibility ensures widespread use in neuro-oncology.

Details
Glioblastoma
Glioblastoma
Human
Female
NOG
Mutated Genes
ATRX
Mutation: p.N564S
Effect: Missense Variant
*Data provided by DepMap
NF1
Mutation: p.F1247IfsTer18
Effect: Frameshift Variant
Impact: Pathogenic
*Data provided by DepMap
TERT
Effect: Upstream Gene Variant
Impact: Pathogenic & Likely Pathogenic & Uncertain Significance
*Data provided by DepMap
Expression Data (provided by DepMap)
Growth Curve