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CDX

SU-DHL-8

Tumor indication

Lymphoma

Tumor subtype

DLBCL (GCB)

Description

SU-DHL-8 (Lymphoma CDX Model) 

The SU-DHL-8 cell line was derived from diffuse large B-cell lymphoma (DLBCL). It provides a reproducible system for hematology drug discovery. SU-DHL-8 reflects aggressive B-cell malignancy biology. Its consistent growth supports translational lymphoma pipelines. 

Key Features: 

  • Derived from diffuse large B-cell lymphoma. 
  • Represents aggressive B-cell disease. 
  • Suspension culture phenotype. 
  • Tumorigenic in xenografts. 

Applications: 
SU-DHL-8 is used in preclinical testing of novel lymphoma therapies. It supports biomarker validation and drug resistance research. Researchers apply it to study B-cell signaling pathways. Its reproducibility ensures value for translational hematology research.

Details

Tumor indication
Lymphoma
Tumor subtype
DLBCL (GCB)
Organism
Human
Mouse sex
Female
Lumin data
Proteomics, RNA-Seq, WES

Mutated genes

Select a gene to see the variants recorded for this line.

BRAF TP53

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