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CDX

SK-UT-1

Tumor indication

Uterine

Tumor subtype

Uterine Leiomyosarcoma

Description

SK-UT-1 (Uterine Cancer CDX Model) 

The SK-UT-1 line was derived from a uterine leiomyosarcoma. It represents a rare and aggressive form of uterine cancer. SK-UT-1 has been applied in preclinical sarcoma and gynecologic oncology research. Its reproducibility supports translational rare tumor studies. 

Key Features: 

  • Derived from uterine leiomyosarcoma. 
  • Aggressive sarcoma phenotype. 
  • Tumorigenic in xenografts. 
  • Rare tumor biology. 

Applications: 
SK-UT-1 is used in rare tumor drug discovery, particularly in leiomyosarcoma. Researchers apply it in biomarker development and targeted therapy studies. It supports translational pipelines for gynecologic oncology. Its rarity makes it valuable for focused drug testing.

Details

Tumor indication
Uterine
Tumor subtype
Uterine Leiomyosarcoma
Organism
Human
Mouse sex
Female
Lumin data
Proteomics, RNA-Seq, WES

Mutated genes

Select a gene to see the variants recorded for this line.

ALK APC ARID1A ARID1B MSH2 PIK3CA TP53 TSC2

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