CDX
SHP-77
Tumor indication
Lung
Tumor subtype
SCLC
Description
SHP-77 (Lung Cancer CDX Model)
The SHP-77 line was derived from a patient with small cell lung carcinoma (SCLC). It displays neuroendocrine features characteristic of this aggressive cancer subtype. SHP-77 is widely used in preclinical SCLC research. Its stable growth provides reproducibility in oncology pipelines.
Key Features:
- Derived from small cell lung carcinoma.
- Neuroendocrine morphology.
- Highly tumorigenic in xenografts.
- Represents aggressive SCLC biology.
Applications:
SHP-77 is used in studies of cytotoxic and targeted therapies for SCLC. Researchers apply it in biomarker discovery and resistance mechanism research. It is frequently used in neuroendocrine tumor biology studies. Its reproducibility ensures consistency in translational pipelines.
Details
- Tumor indication
- Lung
- Tumor subtype
- SCLC
- Organism
- Human
- Mouse sex
- Female
- Lumin data
- Proteomics
Mutated genes
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Gene expression
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| Gene | Expression |
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Expression measured across the Champions panel.
Lumin data
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