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CDX

RAJI

Description

RAJI (Burkitt’s Lymphoma CDX Model) 

The RAJI line was derived from a patient with Burkitt’s lymphoma. It is Epstein–Barr virus (EBV)-positive, reflecting a clinically relevant subset of this cancer. RAJI has been a standard B-cell lymphoma model in hematology research. Its reproducibility makes it valuable for translational pipelines. 

Key Features: 

  • Derived from Burkitt’s lymphoma. 
  • EBV-positive B-cell line. 
  • Strong growth in xenograft systems. 
  • Suitable for lymphoma drug research. 

Applications: 
RAJI is used in studies of B-cell lymphoma biology and EBV-associated oncogenesis. Researchers apply it in testing cytotoxic and targeted therapies. It supports biomarker and immunotherapy research in Burkitt’s lymphoma. Its stability ensures consistency in hematology pipelines.

Details
Lymphoma
Burkitt's lymphoma
Human
Female
NOG
Mutated Genes
TP53
Mutation: p.R213Q
Effect: Missense Variant
Impact: Likely Pathogenic & Pathogenic & Drug Response & Not Provided
Mutation: p.Y234H
Effect: Missense Variant
Impact: Pathogenic & Likely Pathogenic
Lumin Data
Expression Data
Growth Curve