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CDX

Hs 695T

Tumor indication

Skin

Tumor subtype

Ameloanotic Melanoma

Description

HS 695T (Melanoma CDX Model) 

The HS 695T melanoma line was derived from a metastatic melanoma lesion. It is representative of aggressive melanoma progression. HS 695T has been applied in preclinical research focused on therapy resistance. Its reproducibility makes it a reliable system for translational oncology. 

Key Features: 

  • Derived from metastatic melanoma. 
  • Represents advanced melanoma biology. 
  • Highly tumorigenic in xenografts. 
  • Suitable for resistance mechanism studies. 

Applications: 
HS 695T is used in testing novel therapeutics for metastatic melanoma. It supports drug resistance and biomarker discovery programs. Researchers employ it to investigate mechanisms of tumor progression. Its aggressive phenotype makes it valuable for late-stage melanoma studies.

Details

Tumor indication
Skin
Tumor subtype
Ameloanotic Melanoma
Organism
Human
Mouse sex
Female

Mutated genes

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ATM BRAF NF1 TERT

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