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CDX

Daudi

Description

DAUDI (Burkitt’s Lymphoma CDX Model) 

The DAUDI cell line was derived from a patient with Burkitt’s lymphoma. It represents an Epstein–Barr virus (EBV)-positive B-cell lymphoma model. DAUDI has been a cornerstone for hematology research and drug development. Its growth characteristics make it useful in studying B-cell malignancies and targeted therapies. 

Key Features: 

  • Derived from Burkitt’s lymphoma. 
  • EBV-positive B-cell line. 
  • Strong growth in suspension culture. 
  • Useful for lymphoma drug discovery. 

Applications: 
DAUDI supports studies of B-cell lymphoma biology and immunotherapy evaluation. It is frequently used to test cytotoxic agents and targeted therapies. Researchers employ it to study EBV-associated oncogenesis. Its reproducibility has made it a standard in hematologic oncology research.

Details
Lymphoid
Burkitt's Lymphoma
Human
Female
NOG
Mutated Genes
FANCA
Mutation: p.S103Ter
Effect: Stop-Gain
Impact: Likely Pathogenic
TP53
Mutation: p.G266E
Effect: Missense Variant
Impact: Pathogenic / Likely Pathogenic & Likely Pathogenic & Uncertain Significance
Lumin Data
Expression Data
Growth Curve