<img alt="" src="https://secure.soil5hear.com/223550.png" style="display:none;">
Skip to content

 

Assays

 

 

Champions' analytical testing assays enhance endpoint data collection in preclinical in vivo studies, ex vivo assays, and throughout clinical trial specialty testing. We employ high-parameter flow cytometry to deconvolute diverse cell populations, while immunohistochemistry and plate-based tools assess tissue changes. Next Generation Sequencing and 4D Proteomics can be used to generate hypotheses that drive oncology drug strategy.

A Champions scientist pipetting during an endpoint analysis assay.

Endpoint Analysis

Endpoint analyses form a critical component in both preclinical and clinical oncology research studies. These analyses provide researchers with quantifiable measures to assess the treatment efficacy across multiple parameters and derive safe and accurate insights to guide critical decisions on your programs. Working with Champions gives you access to: 

  • Scientific consultation throughout study design, execution, and data interpretation
  • Competitive turnaround times
  • State-of-the-art analytical laboratories
A Cancer cell with flow cytometry antibodies attaching for analysis.
FLOW CYTOMETRY

Interrogate up to 30 parameters on each individual cell simultaneously within a sample

H&E staining of tissue using histology and immunochemistry techniques.
HISTOLOGY & IMMUNOHISTOCHEMISTRY

Assess target protein expression within a tissue of interest

Scientists pipetting into 96 well plates for Luminex or ELISA assays.
LUMINEX & ELISA

Evaluate secreted proteins such as cytokines, growth factors, and chemokines in plate-based assays

A DNA stand involved in Next Generation Sequencing
NEXT GENERATION SEQUENCING

Generate personalized medicine strategies through bioinformatic and computational analyses

A protein that can be detected using 4D proteomics research.
4D PROTEOMICS

Utilize mass-to-charge ratio, retention time, ionic strength, and ion mobility to identify and quantify proteins

Detection of protein bands using Western Blot Analysis.
WESTERN BLOT

Assess protein expression with picogram level sensitivity in only microliters of sample

Illuminating fluorescence detecting DNA damage using the Comet Assay.
DNA DAMAGE ASSAYS

Measure activity of agents involved in DNA damage repair

High content imaging analysis visualization of TumorGraft3D PDXO cultures.
IMAGING
Evaluate in vivo metastasis and ex vivo tumor infiltration
Scientist calculating Colony forming units (CFU) through a microscope.
COLONY FORMING UNIT (CFU) ASSAY

Measure clonal composition shifts in response to cytotoxic therapies

Evaluation of cell viability of tumor cells in long term culture.
CELL VIABILITY/PROLIFERATION

Evaluate the viability or proliferation of cells throughout the duration of ex vivo assays

DNA is being detected using quantitative PCR
QUANTITATIVE REAL-TIME PCR (QPCR)

Determine the absolute quantity of target DNA in each sample