Systemic AML
In Vivo Screen
Unlock comprehensive insights about your therapeutic in our exclusive cohort of primary patient AML models.
Study Design & Overview
Champions' AML In Vivo Screen features 30 primary models of Acute Myeloid Leukemia (AML), each representing complex AML subtypes to accurately recapitulate disease profiles. Utilizing primary patient models that are never passaged and are systemically engrafted, each model preserves unique patient characteristics.
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Complete model characterization (clinical data, NGS analysis, proteomics, phospho-proteomics, and kinase activity)
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Terminal flow cytometry analysis on peripheral blood and bone marrow
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AML Engraftment Assessement using Champions' Standard systemic AML In Vivo engraftment panel: CD3, CD33, CD34,CD38, mCD45, hCD45, CD117, CD123, Viability Dye
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Plasma-based Luminex available
Champions' Industry-leading Clinical Annotation & Multi-omic Characterization
AML In Vivo Screen: Terminal Bone Marrow Flow Cytometry Results