Luminex / ELISA Assays
Whether you are multiplexing immunoassays through the Luminex platform or evaluating changes in protein expression by ELISA technology, Champions Oncology has the expertise. We have utilized these platforms to evaluate ex vivo samples (e.g. tumor and serum/plasma) from our well characterized PDX tumor bank and can evaluate cell function, establish a mechanism of action and can determine pharmacodynamics. These assays specifically evaluate only secreted proteins, however, intracellular cytokines produced by specific cell types can be evaluated by flow cytometry.
Evaluation by Luminex technology of multiple secreted cytokines from PBMCs either left untreated or activated for 24hr with αCD3/αCD28.