Assays
Champions' analytical testing assays enhance endpoint data collection in preclinical in vivo studies, ex vivo assays, and throughout clinical trial specialty testing. We employ high-parameter flow cytometry to deconvolute diverse cell populations, while immunohistochemistry and plate-based tools assess tissue changes. Next Generation Sequencing and 4D Proteomics can be used to generate hypotheses that drive oncology drug strategy.
Endpoint Analysis
Endpoint analyses form a critical component in both preclinical and clinical oncology research studies. These analyses provide researchers with quantifiable measures to assess the treatment efficacy across multiple parameters and derive safe and accurate insights to guide critical decisions on your programs. Working with Champions gives you access to:
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Scientific consultation throughout study design, execution, and data interpretation
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Competitive turnaround times
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State-of-the-art analytical laboratories
FLOW CYTOMETRY
Interrogate up to 30 parameters on each individual cell simultaneously within a sample
HISTOLOGY & IMMUNOHISTOCHEMISTRY
Assess target protein expression within a tissue of interest
LUMINEX & ELISA
Evaluate secreted proteins such as cytokines, growth factors, and chemokines in plate-based assays
NEXT GENERATION SEQUENCING
Generate personalized medicine strategies through bioinformatic and computational analyses
4D PROTEOMICS
Utilize mass-to-charge ratio, retention time, ionic strength, and ion mobility to identify and quantify proteins
WESTERN BLOT
Assess protein expression with picogram level sensitivity in only microliters of sample
DNA DAMAGE ASSAYS
Measure activity of agents involved in DNA damage repair
IMAGING
COLONY FORMING UNIT (CFU) ASSAY
Measure clonal composition shifts in response to cytotoxic therapies
CELL VIABILITY/PROLIFERATION
Evaluate the viability or proliferation of cells throughout the duration of ex vivo assays
QUANTITATIVE REAL-TIME PCR (QPCR)
Determine the absolute quantity of target DNA in each sample