
The patient-derived tumor bank built for the biology others cannot model
We give preclinical oncology researchers a living bank of over 1,400 patient-derived models, many from late-stage, metastatic tumors and characterized across the genome, transcriptome and proteome, so you select on real data and trust that a result reflects the tumor it came from.
The Bank. The Data. The Science
Built on real biology. Proven over 20 years.
Models that reflect the patient
Over 1,400 patient-derived models, with more than 700 pretreated tumors, in low-passage, so the biology you study still behaves like the tumor it came from.
Deep data
Every model carries multi-omic, clinical-response, and proprietary functional data, real tumor biology, ready for computation, so your data scientists train predictive models on ground truth, not inference.
The science runs on the same models, by the same team
The same scientific group that characterizes every model, across the genome, transcriptome, and proteome, runs the in vivo and ex vivo work on it. Your data stays consistent from model selection through analysis
Welcome
Meet Champions Oncology
Champions was built on an observation most preclinical research ignores: the patients in your trial will not be treatment naive, but most preclinical models are. Since 2007, we have banked tumors from metastatic, heavily pretreated patients, documented each donor’s treatment history, and characterized models across the genome, transcriptome, and proteome. The result is a preclinical study you can stand behind when the program reaches the clinic.
Featured
Popular Content

On Demand Webinar
Mastering ADC Model Selection and Navigating Resistance
Antibody-drug conjugates are moving fast, and so is the science behind choosing the right model to develop them. Target expression alone doesn't tell the full story as tumors vary in target density within themselves and across patients, and even a well-selected model can eventually face resistance.

Service
Build Confidence in Your Radiopharmaceutical Program
From radiochemistry and in-house SPECT/CT imaging to PDX efficacy and biodistribution, Champions Oncology delivers one coordinated, U.S.-based workflow to move from construct to decision faster.
Service
KRAS Preclinical Platform
We have built a bespoke KRAS platform with clinically relevant tumor models, in vivo daraxonrasib response data, direct measurement of the molecular systems driving response, and a way to translate resistance biology into development decisions.

Lumin
Leverage the Power of Lumin
Testimonials
"Champions is a great CRO to partner with. They are always on time, flexible to meet our needs, and are experts in PDX models."
Sr. Director, Biotech Company
"I've been an active Lumin user for over a year now. It's been critical to use this software to analyze and visualize our multi-omic datasets from Champions."
Sr. Bioinformatician, Pharmaceutical Company
"Champions is a great CRO to partner with. They are always on time, flexible to meet our needs, and are experts in PDX models."
Sr. Director, Biotech Company
Newsroom
What's new at Champions


Poster
Development of Robust Evaluation of T Cell Subsets with T-Cell Activation In a 3D Tumor–PBMC Co-Culture Model Enables Reliable Phenotyping and Cytotoxicity Assessment
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Case Study
Assessment of Clinically Approved HER2-Targeted ADCs in Champions’ TumorGraft3D Models
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