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Hematologic Malignancies: Immunogenomic Landscape and Prognostic Tools

Hematologic malignancies are blood cancers that can affect a wide range of blood cells. Malignant cells usually begin proliferating in the bone marrow, and this expansion of abnormal blood cells can lead to significant alterations in the function of the blood and immune system. Hematologic malignancies are typically categorized by cell type and generally classified as leukemias, lymphomas, and myelomas. Here, we provide overview of several of the most hematologic malignancies and highlight cutting edge technologies being used to understand these blood cancers and applying these insights toward the development of novel therapeutics and diagnostics.