TumorGraft® Database

The TumorGraft® Database is Champions' online, searchable database that contains key data on PDX tumor models. We have enhanced details on the molecular features of our models, including gene mutations identified through Whole Exome Sequencing and gene expression levels quantified using RNASeq technology, making the TumorGraft® Database the most annotated compendium of patient-derived xenograft (PDX) models available for searching through a web-based interface.

Users can:

  • Review RNA sequencing and Whole Exome sequencing data for model selection
  • Compare cohorts of well-characterized models
  • See graphical representations of model sets
  • Build complex queries on the indication, clinical data, patient treatment history, or molecular characterizations such as mutations, gene expression, copy number variations (CNV), or gene fusions